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Biofreeze FAQ:

Biofreeze Frequently asked questions

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Q: What are the indications and directions for use of Biofreeze Pain Reliever?

A: Biofreeze Pain Reliever provides temporary relief from minor aches and pains of sore muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains. Apply Biofreeze Pain Reliever to the affected area not more than 4 times daily; massage not necessary.


Q: Where can I buy Biofreeze?

A: Biofreeze products are formulated for authorized distribution through hands-on healthcare practitioners for the patients, clients, and athletes under their care. To find a seller of Biofreeze in your area visit


Q: Do I need a prescription to get Biofreeze?

A: No, you do not need a prescription, nor do you need to be a patient of a healthcare professional in your area to purchase Biofreeze from them. Biofreeze is only available through authorized dealers. Biofreeze is not available through retail outlets or pharmacy locations.


Q: How does Biofreeze work?

A: Biofreeze products are classified as topical analgesics, which work through a ‘counter irritant’ mechanism. This means that the menthol in Biofreeze creates a sensation that overrides pain signals to the brain. This process is known as ‘Gate Control Theory’, where nerve impulses from one stimulus block the nerves containing pain signals to the brain. Recent research also suggests that menthol may stimulate cold receptors in the skin that may help regulate pain as well.


Q: Is Biofreeze commonly used?

A: Yes, Biofreeze is the #1 used and recommended topical pain reliever by chiropractors, massage therapists, physical therapists, and podiatrists.


Q: How often can I use Biofreeze?

A: Biofreeze can be used up to four times a day.


Q: Can you send me a sample of Biofreeze?

A: FREE Biofreeze gel sample packets are available through healthcare practitioners in the United States, including a brochure about the product and a 3 mL trial packet. To get a free sample, find the nearest sample provider by Clicking Here.


Q: What is cryotherapy?

A: Also known as ‘cold therapy’, cryotherapy is the application of cold to temporarily relieve pain. The related term cryokinetics refers to the pairing of pain-relieving cryotherapy with exercise. This cooling and re-warming of tissue stimulates the return of blood flow to the affected areas.

The most common form of cryotherapy is ice. Biofreeze produces the same sensation of cold that accompanies icing. But unlike ice, Biofreeze products allow you to remain active during treatment.


Q: Are there scientific studies done on Biofreeze?

A: Yes, Biofreeze conducts all FDA required studies such as: skin sensitization, drug stability, and process validation testing. We also conduct an additional battery of tests in our laboratory. Lastly, we conduct studies with clinicians to further understand our products. These studies can be found at


Q: Can I take Biofreeze on an airplane?

A: Yes, you can take the 3 fl oz roll-on and 3 mL sample packet on an airplane.


Q: Can you give me the name of a medical distributor in my area?

A: No, we do not have access to that information. Medical distributors do not sell directly to patients and have requested that we do not give out this information. Please contact customer service to get information on distributors in your area.



Q: Can I buy the larger bottle sizes of the Biofreeze?

A: The larger sizes of Biofreeze are designed for in clinic use.


Q: Is Biofreeze available in stores or through the Internet?

A: Biofreeze is only sold through hands-on healthcare professionals, not in retail stores. Some clinicians do sell Biofreeze on through their website. To locate a practitioner in your area please go to


Q: Do you have any studies about long-term use of Biofreeze?

A: Biofreeze is an over the counter topical analgesic pain relieving gel used to provide temporary relief from minor aches and pains of sore muscles and joints associated with simple backache, arthritis, bruises, strains and sprains. It is labeled according to the Food and Drug Administration (FDA) regulations regarding topical analgesics. All ingredients, directions for use, and product warnings are listed on the label.

Please remember that Biofreeze is a topical pain reliever, not a cure to an underlying condition. It provides temporary pain relief. If you have any questions regarding the product or its use, please consult your healthcare Professional. If condition worsens or symptoms persist for more than 7 days consult a doctor.


Q: How long does Biofreeze last, when is the expiration date?

A: The product’s shelf life is 2 years. The expiration date can be located on the package of Biofreeze Pain Relieving Product.


Q: What is the active ingredient in Biofreeze?

A: The active ingredient in Biofreeze is menthol.


Q: When was Biofreeze invented?

A: Biofreeze was first introduced in 1991 by a healthcare practitioner that was searching for a way to help his grandmother manage her arthritis pain. Today, Biofreeze products provide relief to countless arthritis sufferers. But the pain reliever’s unique, cooling formulation is also comforting to sore muscles and muscle sprains; easing back shoulder and neck pain; reducing painful ankle, knee, hip, and elbow joints and helping to lessen the effects of muscular strain.


Q: Does Biofreeze contain gluten, starch, aspirin or nut derivatives?

A: No


Q: Will Biofreeze cause any adverse effects if I am taking other medications?

A: Biofreeze is only a topical pain reliever and has a low potential for absorption. We do suggest that you always check with your healthcare professional before using Biofreeze.



Q: If I am Pregnant or nursing – Can I use Biofreeze?

A: Consult a healthcare professional before use.


Q: Can I use a heating pad while also using Biofreeze?

A: No, you should never use a heating pad while using Biofreeze. Biofreeze works by causing a cooling effect, not heat. By using a heating pad in conjunction with Biofreeze, you may cause serious injury to yourself. You may not be able to tell how hot the heating pad is on the problem area, even possibly causing yourself to experience severe blistering.


Q: Can I wrap the area where I have used the Biofreeze?

A: No. You should not wrap or bandage the area where Biofreeze is being applied.


Q: Biofreeze in the EYE – how should I treat this?

A: Rinse eyes with lukewarm water or take a warm shower with the shower water hitting your forehead and running down through your eyes. Do this for 15 minutes. If problem persists, see a physician and be sure to take the Biofreeze with you.


Q: Can I use Biofreeze to cool sunburn pain, in a tanning bed or sauna?

A: Biofreeze is not intended for use in these types of situations.


Q: Can I use Biofreeze on insect bites or for poison ivy?

A: Biofreeze is not intended for use in these types of situations.


Q: Will Biofreeze work on headaches?

A: Biofreeze is not intended for this use.


Q: My child or pet ate Biofreeze, what do I do?

If accidentally ingested, get medical help or contact a Poison Control Center immediately.

Pet – Contact your veterinarian immediately.


Q: Can I use Biofreeze on an open wound or stitches?

A: No, do not apply to wounds or damaged skin.


Q: After applying Biofreeze, I have developed a rash/irritation on my skin. What should I do?

A: Take a tepid (warm) bath with one cup of Arm and Hammer baking soda, or other brand of baking soda. Relax for at least 20 minutes. If rash persists, contact your physician.


Q: Is Biofreeze registered with the FDA?

A: Yes, The FDA registers the facilities that manufacture Biofreeze. Please refer to the National Drug Code number that is on every Biofreeze product. This number represents to the FDA, our product/brand and the actual size of the container.


Q: Is there Aspirin in Biofreeze?

A: No


Q: Is there Capsaicin in Biofreeze?

A: No


Q: Can I use Biofreeze if I have Diabetes?

A: Yes, Biofreeze is a topical pain reliever has a low potential for absorption. Diabetes is a disease in which the body cannot use sugar normally. When diagnosed with this particular ailment, you must be extremely cautious when using any OTC medications. There are certain ingredients in OTC medications that do go in to the bloodstream that can cause a severe reaction to the Diabetic patient. Biofreeze does not contain any of these ingredients and can often be used by the diabetic patient. However, please consult with your healthcare professional before use of the product.


Q: Is Biofreeze vegetarian friendly?

A: Yes Biofreeze is vegetarian friendly, no animal products are used in the ingredients. Biofreeze is also not animal tested.




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